Glutamine has been shown to reduce insulin resistance and high blood sugar in animal studies. In other words, it prevents the development of glucose regulation problems.
Glutamine does this through several mechanisms. When your blood sugar is low, glutamine suppresses insulin to stop a further decline of blood sugar levels. It also stimulates glycogen to be released to help increase the blood sugar to normal levels. Further, glutamine is a special "glycogenic amino acid," which means it can be converted by the body to sugar for energy production through a biochemical process called "gluconeogenesis."
In effect, glutamine helps prevent hypoglycemia because it is converted to glucose inthe liver when your blood sugar is low. So glutamine serves as a noncarbohydrate source of energy for the body. When you don't eat sugar or carbohydrates, having abundant glutamine in the diet or through supplementation will mean that less muscle tissue will be broken down to provide glucose when you need it.